Mycotic renal artery degeneration and systemic sepsis caused by infected renal artery stent
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Use of a Hanging-weight System for Isolated Renal Artery Occlusion
Published on: July 19, 2011
C A DeMaioribus1, C A Anderson, S S Popham
1Department of Surgery, Tripler Army Medical Center, Honolulu, Hawaii, USA.
Abstract:
A case of Staphylococcus aureus renal artery stent infection was studied. Fourteen days after the procedure, the patient had a fever, hypotension, and an elevated white blood cell (WBC) count. Blood cultures were positive for S. aureus on admission and during the patient's hospitalization, despite intravenous vancomycin therapy. Evaluation included serial CT scans, revealing increasing persistent inflammation with development of multiple renal intraparenchymal abscesses, and arteriography, showing marked degeneration of the renal artery. Therapy required resection of the renal artery/stent and nephrectomy. This case confirms the severe nature of S. aureus stent infection; we recommend prophylactic antibiotics before these procedures, as well as expeditious evaluation and consideration for aggressive surgical therapy if this complication is suspected.
Insights
Staphylococcus aureus can cause severe renal artery stent infections, leading to abscesses and artery degeneration. Prompt surgical intervention is crucial for managing this serious complication.
Area of Science:
- Nephrology
- Infectious Diseases
- Vascular Surgery
Background:
- Renal artery stenting is a common procedure for renovascular hypertension.
- Stent infections, though rare, pose significant risks to patient health.
- Staphylococcus aureus is a notable pathogen in hospital-acquired infections.
Observation:
- A patient developed fever, hypotension, and elevated white blood cell count 14 days post-stenting.
- Blood cultures persistently showed Staphylococcus aureus despite vancomycin treatment.
- Serial CT scans revealed progressive inflammation and renal abscesses; arteriography showed renal artery degeneration.
Findings:
- The case highlights a severe Staphylococcus aureus infection of a renal artery stent.
- Infection led to the development of multiple intra-renal abscesses and significant arterial damage.
- Standard antibiotic therapy proved insufficient to clear the infection.
Implications:
- This case underscores the critical need for vigilance regarding stent infections.
- Prophylactic antibiotics before renal artery stenting may help prevent such infections.
- Early recognition and aggressive surgical management, including stent removal and nephrectomy, are vital for successful outcomes.
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