Mycotic renal artery degeneration and systemic sepsis caused by infected renal artery stent

C A DeMaioribus1, C A Anderson, S S Popham

  • 1Department of Surgery, Tripler Army Medical Center, Honolulu, Hawaii, USA.

Journal of Vascular Surgery
|September 16, 1998
PubMed

Insights

Staphylococcus aureus can cause severe renal artery stent infections, leading to abscesses and artery degeneration. Prompt surgical intervention is crucial for managing this serious complication.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Renal artery stenting is a common procedure for renovascular hypertension.
  • Stent infections, though rare, pose significant risks to patient health.
  • Staphylococcus aureus is a notable pathogen in hospital-acquired infections.

Observation:

  • A patient developed fever, hypotension, and elevated white blood cell count 14 days post-stenting.
  • Blood cultures persistently showed Staphylococcus aureus despite vancomycin treatment.
  • Serial CT scans revealed progressive inflammation and renal abscesses; arteriography showed renal artery degeneration.

Findings:

  • The case highlights a severe Staphylococcus aureus infection of a renal artery stent.
  • Infection led to the development of multiple intra-renal abscesses and significant arterial damage.
  • Standard antibiotic therapy proved insufficient to clear the infection.

Implications:

  • This case underscores the critical need for vigilance regarding stent infections.
  • Prophylactic antibiotics before renal artery stenting may help prevent such infections.
  • Early recognition and aggressive surgical management, including stent removal and nephrectomy, are vital for successful outcomes.

Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...