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Updated: Aug 18, 2026

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
[Unusual metastasis of a malignant pleural mesothelioma]
M Leutz1, D Ukena, G W Sybrecht
1Medizinische Universitätsklinik, Innere Medizin V, Universitätskliniken des Saarlandes. pnmleu@krzsun.med-rz.uni-sb.de
Abstract:
Usually malignant pleural mesothelioma causes pain and dyspnoea due to local invasion of the chest wall and compression of the lung. Distant metastases rarely cause symptoms. We report on a patient with an epithelial subtype of malignant pleural mesothelioma who presented himself after chemo- and immunotherapy with shortness of breath and loss of weight due to a temporo-mandibular joint and a new nodular shadow in the contralateral lung. The prior diagnosis of an epithelial subtype of pleural mesothelioma was confirmed histologically in a pleural biopsy as well as in the resected orofacial metastases.
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