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Related Experiment Videos

Plasma prolactin levels during pregnancy

S Biswas, C H Rodeck

    British Journal of Obstetrics and Gynaecology
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Plasma prolactin levels during pregnancy were measured using radioimmunoassay. While some abnormal levels were noted in complicated pregnancies, prolactin did not prove to be a reliable indicator of maternal or fetal well-being.

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    Area of Science:

    • Reproductive Endocrinology
    • Clinical Chemistry

    Background:

    • Plasma prolactin levels naturally increase during pregnancy.
    • Monitoring hormonal changes is crucial for understanding pregnancy outcomes.

    Purpose of the Study:

    • To determine plasma prolactin levels in pregnant women.
    • To assess the correlation between prolactin levels and pregnancy complications.

    Main Methods:

    • Radioimmunoassay (RIA) was used to measure plasma prolactin.
    • Samples were collected from uncomplicated and complicated pregnancies (8-40 weeks gestation).

    Main Results:

    • Normal pregnancy prolactin ranged from 6 ng/ml to 210 ng/ml.
    • Elevated prolactin was observed in 14% of threatened abortion cases and 7% of hypertension cases.

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  • Lower prolactin levels were associated with low urinary estrogen excretion.

    • Conclusions:

    • Plasma prolactin levels show variability in normal and complicated pregnancies.
    • Prolactin levels are not a definitive marker for maternal or fetal health assessment.