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Updated: Aug 7, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

[Passive smoking and other risk factors associated to the lower respiratory illnesses in sucking infants]

F Galve Royo1, C García Vera, F J Rubio Sevillano

  • 1Centro de Salud Teruel.

Atencion Primaria
|September 19, 1998
PubMed

Insights

Passive smoking, older siblings, and male sex significantly increase lower respiratory illness (LRIs) risk in infants. Shorter breastfeeding durations also correlate with higher LRI incidence during the first year of life.

Area of Science:

  • Pediatrics
  • Epidemiology
  • Public Health

Context:

  • Lower respiratory illnesses (LRIs) are a significant cause of infant morbidity.
  • Identifying risk factors is crucial for prevention strategies.
  • This study examines LRI prevalence and associated factors in infants within their first year of life.

Purpose:

  • To evaluate the frequency of LRIs in the first year of life.
  • To determine the relationship between LRIs and risk factors including passive smoking, feeding methods, and family structure.
  • To assess the impact of sex on LRI incidence.

Summary:

  • A retrospective study of 240 infants found that 37% experienced at least one LRI episode in their first year.
  • Key risk factors identified include passive smoking (OR=1.86), exclusive breastfeeding for less than 5 months (OR=2.1), and having older siblings (OR=3.12).
  • Male infants showed a statistically significant higher number of LRI episodes compared to females (p=0.0489).

Impact:

  • Findings highlight the critical role of environmental factors like passive smoking and socioeconomic factors like family structure in infant respiratory health.
  • Results underscore the protective effect of adequate breastfeeding duration.
  • The study provides evidence for targeted public health interventions to reduce LRI burden in infants.
Abstract

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