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Updated: Jun 29, 2026

A Simple Fluorescence Assay for Quantification of Canine Neutrophil Extracellular Trap Release
Published on: November 21, 2016
[Sensitivity of resonance thrombograms in thrombocytopenia of dogs]
Abstract:
Based on results of 84 blood samples, taken from 28 dogs suffering from thrombocytopenia, the resonance thrombography turned out as a method with low sensitivity (S) to detect thrombocytopenia in dogs. It was insignificant which one of the two tested resonance thrombographs was taken for measurement and which parameter of the resonance thrombogram (RTG) was used for the thrombocytic potential of haemostasis, the amplitude (RTG-P) or descending time of the platelet side. Only samples containing < or = 25,000 platelets/microliter were reliably measured (S > or = 0.90), whereas thrombocytopenias with > 50,000 platelets/microliter usually resulted in false negative results. The correlation between the platelet count and RTG-P could be almost expressed by a geometrical regression (rs = -0.709). The low sensitivity of RTG mirrors the multifactorial influences and contrasts to the exclusive use of RTG in the screening of thrombocytopenia.

