Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chlamydia pneumoniae and asthma

P J Cook1, P Davies, W Tunnicliffe

  • 1Department of Respiratory Medicine, City Hospital, Birmingham, UK.

Thorax
|September 19, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systematic review: chronic obstructive pulmonary disease and work-related outcomes.

Occupational medicine (Oxford, England)·2018
Same author

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study; response to comments.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2017
Same author

Patterns of domestic exposure to carbon monoxide and particulate matter in households using biomass fuel in Janakpur, Nepal.

Environmental pollution (Barking, Essex : 1987)·2016
Same author

Cohort Profile: The Birmingham Chronic Obstructive Pulmonary Disease (COPD) Cohort Study.

International journal of epidemiology·2016
Same author

A systematic review of associations between environmental exposures and development of asthma in children aged up to 9 years.

BMJ open·2014
Same author

Voice disorders in Nigerian primary school teachers.

Occupational medicine (Oxford, England)·2014
Same journal

Mediastinal amyloidosis mimicking advanced lung cancer.

Thorax·2026
Same journal

Comparative performance of endobronchial ultrasound-guided sampling techniques in patients with mediastinal lesions: a network meta-analysis.

Thorax·2026
Same journal

Vitamin A and D impact on lung function: differential or common effects across the lifespan?

Thorax·2026
Same journal

The impact of vitamins A and D on lung function and regulatory epigenetics in adult and childhood asthma.

Thorax·2026
Same journal

Radiological factors associated with the recurrence of <i>Mycobacterium avium complex</i> pulmonary disease: a multicentre retrospective cohort study.

Thorax·2026
Same journal

Daughter vesicles in primary diaphragmatic hydatid cyst.

Thorax·2026
See all related articles

Chlamydia pneumoniae infection is not significantly associated with acute asthma. However, previous infection with Chlamydia pneumoniae was strongly linked to severe chronic asthma in a multi-racial population.

Area of Science:

  • Infectious Diseases
  • Respiratory Medicine
  • Epidemiology

Background:

  • The association between Chlamydia pneumoniae infection and asthma has been previously suggested.
  • Potential confounding factors may influence this observed association.

Purpose of the Study:

  • To investigate the association between Chlamydia pneumoniae infection and asthma.
  • To adjust for potential confounding variables in a multi-racial population.

Main Methods:

  • Antibody levels to Chlamydia pneumoniae were measured using microimmunofluorescence.
  • Patients included those with acute asthma, severe chronic asthma, and controls.
  • Logistic regression analysis was employed to control for confounders such as ethnicity, age, sex, smoking, steroid use, diabetes, and social deprivation.

Related Experiment Videos

Main Results:

  • No significant difference in acute or previous Chlamydia pneumoniae infection was found between acute asthma patients and controls.
  • A statistically significant association was observed between previous Chlamydia pneumoniae infection and severe chronic asthma (adjusted odds ratio: 3.99).

Conclusions:

  • The findings challenge previously reported associations between Chlamydia pneumoniae infection and asthma.
  • Future research should specifically consider the role of severe chronic asthma in the context of Chlamydia pneumoniae infection.