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Updated: Aug 8, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
A comparison of three methods of analgesia in children having day case circumcision
1Department of Anaesthesia, Royal Liverpool Children's Hospital NHS Trust (Alder Hey), UK.
Insights
Diclofenac suppositories alone provided less pain relief for circumcised boys than a penile block with diclofenac. Combining a penile block with diclofenac offers optimal pain management for pediatric circumcision.
Area of Science:
- Pediatric Surgery
- Pain Management
- Anesthesiology
Background:
- Circumcision is a common pediatric surgical procedure.
- Effective pain management is crucial for optimizing patient outcomes and parental satisfaction following circumcision.
- Various analgesia methods are employed, but optimal strategies require further investigation.
Purpose of the Study:
- To compare the efficacy of different analgesia methods for day case circumcision in children.
- To evaluate pain scores and parental-reported outcomes following three distinct pain management protocols.
Main Methods:
- Sixty-one children undergoing day case circumcision were randomized into three groups.
- Group 1: Penile block. Group 2: Penile block plus diclofenac suppository. Group 3: Diclofenac suppository alone.
- Pain was assessed using the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) at multiple time points, with parental follow-up for two days.
Main Results:
- No significant differences in pain scores or outcomes were observed between groups at one and two hours post-awakening, or in parental follow-up.
- However, in the recovery area, Group 3 (diclofenac suppository alone) exhibited higher pain scores and more crying compared to Group 2 (penile block plus diclofenac).
Conclusions:
- A penile block combined with a diclofenac suppository appears to be more effective in immediate post-operative pain control than a diclofenac suppository alone for pediatric circumcision.
- While overall pain scores and parental satisfaction were similar across groups over two days, the combination approach offers superior acute pain relief in the recovery setting.
Abstract:
Sixty-one children were randomized to receive one of three methods of analgesia for day case circumcision. Group 1 received a penile block, group 2 received a penile block plus diclofenac suppository and group 3 received a diclofenac suppository alone. CHEOPS pain scoring was performed in the recovery area, one h after awakening and two h after awakening. There was no difference between the groups except in the recovery area when group 3 cried more and had a higher pain score than group 2. Parental follow-up questionnaires for the subsequent two days showed no difference in measured parameters between the groups.
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