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[Diffuse aspiration bronchiolitis in an elderly woman]

I Sugama1, K Simoji, M Touyama

  • 1Yonabaru-chuo-Hospital, Japan.

Nihon Kokyuki Gakkai Zasshi = the Journal of the Japanese Respiratory Society
|September 22, 1998
PubMed
Summary

Persistent nocturnal coughing in an elderly woman was linked to diffuse aspiration bronchiolitis. Micro-aspiration of oral secretions during sleep, involving Actinomyces bacteria, was identified as the cause.

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Area of Science:

  • Pulmonology
  • Microbiology
  • Pathology

Background:

  • Nocturnal coughing and abnormal chest X-rays prompted investigation in a 74-year-old female patient.
  • Initial transbronchial lung biopsy revealed nonspecific inflammatory changes, necessitating further examination.

Observation:

  • Chest X-rays demonstrated cavities in the right upper lobe and nodular shadows in multiple lung fields.
  • Open-lung biopsy was performed for a definitive histopathological diagnosis.

Findings:

  • Histopathology confirmed diffuse aspiration bronchiolitis.
  • The presence of Actinomyces, a common oral bacterium, was identified as a key factor.

Implications:

  • The findings suggest micro-aspiration of oro-pharyngeal secretions during sleep as a cause of diffuse aspiration bronchiolitis.

Related Experiment Videos

  • This highlights the importance of considering oral flora in respiratory infections, particularly in elderly patients with nocturnal symptoms.