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Published on: August 22, 2012
Hepatic amebiasis among patients in a public teaching hospital
W X Shandera1, P Bollam, R H Hashmey
1Department of Internal Medicine, Baylor College of Medicine, Ben Taub General Hospital, Houston, Tex 77030, USA.
Abstract:
The increase in immigration to the United States is associated with diseases, such as amebiasis, that are endemic to developing countries. We retrospectively reviewed 49 public-hospital patients with hepatic amebiasis occurring between 1985 and 1995. Most patients were immigrants (47) from Latin America (43), male (43), and young (mean age, 39.8 years). Symptoms noted by more than half were abdominal pain and fever. Ultrasonography showed single lesions in 70% and right-sided involvement in 85%. Serologies against Entamoeba histolytica were noted in 86%. After treatment, the median interval from admission to defervescence was 2 days, to normalization of white cell count 3 days, and to resolution of abdominal pain 4 days. Morbidity (one case of pericarditis) and mortality (one death in a cirrhotic man) were low. Hepatic amebiasis continues to be diagnosed in the United States, primarily among Hispanic and Asian immigrants. When appropriately considered, current diagnostic and therapeutic modalities result in rapid improvement and excellent outcome.
Insights
Hepatic amebiasis, a parasitic infection, is increasingly diagnosed in the US, primarily affecting immigrants. Prompt diagnosis and treatment lead to rapid recovery and excellent outcomes for patients with this disease.
Area of Science:
- Infectious Diseases
- Hepatology
- Public Health
Background:
- Increased immigration to the US is linked to imported diseases like amebiasis.
- Hepatic amebiasis is a significant parasitic infection endemic in developing countries.
Observation:
- A retrospective review of 49 patients with hepatic amebiasis from 1985-1995 was conducted.
- The majority of patients were immigrants from Latin America, predominantly male, with a mean age of 39.8 years.
- Common symptoms included abdominal pain and fever, with ultrasonography revealing single lesions in 70% and right-sided involvement in 85%.
Findings:
- Entamoeba histolytica serology was positive in 86% of cases.
- Treatment resulted in rapid symptom resolution: defervescence in 2 days, normalized white cell count in 3 days, and pain resolution in 4 days.
- Morbidity and mortality rates were low, with one case of pericarditis and one death in a cirrhotic patient.
Implications:
- Hepatic amebiasis remains a relevant diagnosis in the US, particularly among Hispanic and Asian immigrants.
- Current diagnostic and therapeutic approaches are effective, leading to swift patient improvement.
- Awareness of hepatic amebiasis is crucial for clinicians managing immigrant populations.
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