Related Experiment Videos
Primary peripheral lung carcinoma smaller than 1 cm in diameter
1Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan. jyoshida@east.ncc.go.jp
Chest
|September 22, 1998
Summary
Limited resection for small peripheral lung cancers (≤1 cm) is risky, as over a third show invasive features. Tumor size alone is insufficient to determine eligibility for limited lung cancer surgery.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonary Medicine
Background:
- Limited resection for small peripheral lung cancers is debated due to potential risks.
- Previous studies highlight concerns regarding the safety of limited resection in these cases.
Purpose of the Study:
- To evaluate the feasibility and risks of limited surgery for primary peripheral lung cancers measuring 1 cm or less.
- To determine if tumor size alone is a reliable indicator for limited resection in lung cancer patients.
Main Methods:
- Retrospective review of 1,051 lung cancer patients who underwent surgical resection.
- Analysis of 13 patients with peripheral cN0M0 tumors ≤1 cm who underwent systematic mediastinal dissection.
- Histopathological review of resected specimens.
Main Results:
- Ten adenocarcinomas, one small cell carcinoma, one squamous cell carcinoma, and one carcinoid tumor were identified.
- One adenocarcinoma showed lymphatic/venous invasion and nodal metastasis; another adenocarcinoma and the small cell carcinoma showed lymphatic invasion.
- One small cell carcinoma had segmental lymph node metastasis.
Conclusions:
- Over one-third of peripheral lung cancers ≤1 cm exhibit invasive characteristics.
- Tumor size alone is not a sufficient criterion for selecting patients for limited resection.
- Careful consideration of invasiveness is crucial when deciding on limited resection for small peripheral lung cancers.