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Discordance of technetium-99m-HMPAO and technetium-99m-ECD SPECT in herpes simplex encephalitis
H Rieck1, C Adelwöhrer, K Lungenschmid
1Department of Neurology, Landesnervenklinik Linz, Austria.
Abstract
Unlabelled:
Technetium-99m-hexamethyl propyleneamine oxime (HMPAO) and 99mTc-ethyl cysteinate dimer (ECD) accumulate in brain tissue in proportion to regional cerebral blood flow in healthy subjects and in patients with a variety of neurological diseases. We report on four patients with herpes simplex encephalitis and the discordance between these two approved cerebral perfusion imaging radiopharmaceuticals.
Conclusion:
SPECT images showed unilateral regional increase of 99mTc-HMPAO uptake and decrease of 99mTc-ECD uptake in the affected temporal lobe.