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Spontaneous remission in patients with essential blepharospasm and Meige syndrome
1Neuro-Ophthalmology Unit, The Wilmer Eye Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.
Purpose:
To determine the frequency of remission in patients with essential blepharospasm and Meige syndrome.
Method:
Retrospective analysis of patients by means of questionnaire in an institutional setting.
Results:
Among 238 patients diagnosed in a single institution as having essential blepharospasm or Meige syndrome, 27 (11.3%) claimed to be symptom free without curative surgery. The average time between onset and resolution in the patients who claimed remission was 4.85 years (range, 3 months to 22 years). Among these patients, the duration of remission averaged 6.33 years (range, 1 year to 14 years).
Conclusion:
Patients with essential blepharospasm or Meige syndrome have a small but definite potential for spontaneous remission of symptoms, particularly within the first 5 years after onset of symptoms.