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Mianserin hydrochloride: a novel antidepressant

A Coppen, R Gupta, S Montgomery

The British Journal of Psychiatry : the Journal of Mental Science

|October 1, 1976

Abstract:

The antidepressant activities of mianserin hydrochloride were investigated and compared with those of amitriptyline. The therapeutic efficacy of the two drugs appeared similar, but the incidence of side-effects was significantly higher with amitriptyline. Plasma levels of mianserin were determined during the trial and were not related to the therapeutic activity of the drug.

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