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Study on interaction of proteins isolated from epithelial cervical tissue with glucocorticoid-response element of
E Poreba1, A Goźdicka-Józefiak, H Kedzia
1Institute of Molecular Biology and Biotechnology, University of Poznań, Poland.
European Journal of Gynaecological Oncology
|September 23, 1998
Abstract:
Genital HPV16 has tropism to cervical epithelial tissue which is highly steroid hormone dependent. Protein/DNA interaction with the fragment of viral DNA containing the glucocorticoid-response element (GRE/PRE) did not indicate the proteins which can bind to the GRE element in normal epithelial cervical tissue. NFI is one of the cellular factors which can participate in the transcription of viral genes in study tissue.