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Clinical development in the management of lupus in the neonate, child, and adolescent
1Pediatric Rheumatology, Children's Hospital San Diego, CA 92123-8082, USA.
Current Opinion in Rheumatology
|September 25, 1998
Insights
This review covers antiphospholipid syndrome in children and neonatal lupus syndrome. It also summarizes new management strategies for pediatric systemic lupus erythematosus.
Area of Science:
- Pediatric Rheumatology
- Immunology
Background:
- Systemic lupus erythematosus (SLE) in children presents unique challenges.
- Antiphospholipid syndrome (APS) is a significant concern in pediatric SLE.
- Neonatal lupus syndrome (NLS) requires specific diagnostic and management approaches.
Purpose of the Study:
- To review recent advancements in the understanding and management of pediatric SLE.
- To focus on antiphospholipid syndrome (APS) in children.
- To detail neonatal lupus syndrome (NLS) and summarize novel therapeutic strategies for pediatric SLE.
Main Methods:
- Literature review of pediatric systemic lupus erythematosus.
- Focus on antiphospholipid syndrome and neonatal lupus syndrome.
- Synthesis of current management approaches for pediatric SLE.
Main Results:
- Recent literature highlights the spectrum and management of APS in children.
- Detailed discussion of neonatal lupus syndrome is provided.
- Newer management strategies for pediatric SLE are summarized.
Conclusions:
- Understanding APS and NLS is crucial for managing pediatric SLE.
- Evolving therapeutic strategies offer improved outcomes for children with SLE.
- This review provides a comprehensive update on pediatric SLE management.
Abstract:
The recent literature in pediatric aspects of systemic lupus erythematosus has focused primarily on the spectrum and management of antiphospholipid syndrome in children; this review summarizes developments in this area. In addition, the neonatal lupus syndrome is discussed in detail, and newer approaches to the management of children and adolescents with systemic lupus erythematosus will be summarized.