Peptides from pigeon cerebrum: two-dimensional fingerprinting and amino acid analysis

The number and heterogeneity of endogenous peptides from pigeon cerebrum were studied by two-dimensional peptide fingerprinting. A highly consistent pattern of 8-9 peptides in the 1000-5000 molecular weight range was obtained from each cerebral sample. Amino acid analysis of the peptide material indicated that 30% of the identified residues were dicarboxylic amino acids and 30% were alphatic amino acids. There was no evidence for the presence of arginine or half-cystine in the peptide fraction.