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Antimalarial principles from Artemisia indica
R Chanphen1, Y Thebtaranonth, S Wanauppathamkul
1National Center for Genetic Engineering and Biotechnology (BIOTEC)/National Science and Technology Development Agency (NSTDA), Rama 6 Road, Bangkok 10400, Thailand.
Journal of Natural Products
|September 28, 1998
Abstract:
Activity-guided investigation of Artemisia indica Willd. has led to isolation of exiguaflavone A, exiguaflavone B, maackiain, and 2-(2, 4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran. Exiguaflavones A and B exhibit in vitro antimalarial activities of 4.60 x 10(-6) and 7.05 x 10(-6) g/mL, respectively, against Plasmodium falciparum.