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[Risk factors for ischemic heart disease in patients with chronic fatigue syndrome]
Z Vilikus1, H Marecková, I Janatková
1Ustav tĕlovýchovného lékarství a Ustav klinické imunologie 1. lékarské fakulty Univerzity Karlovy, Praha, Czech Republic. zdenek vilikus@medicom.cz
Insights
Individuals with chronic fatigue syndrome (CFS) do not exhibit higher coronary artery disease (CAD) risk factors compared to healthy individuals. Lower exercise expenditure in CFS patients did not significantly impact their CAD risk profile.
Area of Science:
- Cardiology
- Internal Medicine
- Epidemiology
Context:
- Chronic Fatigue Syndrome (CFS) is a complex condition with poorly understood long-term health implications.
- Coronary Artery Disease (CAD) is a leading cause of mortality, and understanding risk factors in various patient populations is crucial.
Purpose:
- To compare the risk factors for coronary artery disease (CAD) between patients diagnosed with chronic fatigue syndrome (CFS) and a matched control group of healthy individuals.
- To investigate whether reduced physical activity in CFS patients correlates with increased cardiovascular risk.
Summary:
- A study compared 33 CFS patients with 33 matched healthy controls regarding CAD risk factors.
- Utilizing the Minnesota Questionnaire and Compendium of Physical Activities, researchers assessed total energetic expenditure.
- Findings indicated no significant differences in CAD risk factors, including aerobic fitness, anthropometrics, blood pressure, lipoproteins, uric acid, and smoking habits, between the two groups, despite lower exercise expenditure in CFS patients.
Impact:
- This research suggests that CFS, despite associated lower physical activity levels, may not confer an elevated risk for coronary artery disease.
- Provides valuable insights for clinicians managing CFS patients, potentially alleviating concerns about increased cardiovascular morbidity.
- Highlights the importance of comprehensive risk assessment beyond just physical activity levels in chronic illness management.
Abstract:
Risk factors of coronary artery disease (CAD) between a group of patients suffering of chronic fatigue syndrome (CFS) and a control group of healthy persons (whose exercise activity was not health-limited) were compared. Thirty three patients (27 women, 6 men, average age 39.9 +/- 11.7 years) and the same number of controls matched in age (39.8 +/- 10.3 years), gender and body weight. The Minnesota Questionnaire (by Taylor) and the Compendium of Physical Activities (by Ainsworth) were used to estimate total energetic expenditure in exercise activity as well as in job. The risk factors of CAD in the patients with CFS were not higher than in the control group. Aerobic physical fitness, basic anthropometric data, blood pressure, spectrum of blood lipoproteins, blood uric acid and smoking habits were not different between the compared groups. Patients suffering from CFS had lower total energetic expenditure in exercise activity. Nevertheless, this significant difference in sports activity was not large enough to cause any difference in risk factors of CAD between the CFS patients and the control group.
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