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Updated: Jul 21, 2026
06:39
Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
[Extra-coronary atherosclerosis in documented coronary patients]
M Hodara1, C Bonithon-Kopp, D Courbon
1Service des maladies cardiovasculaires, hôpital Cochin, Paris.
Archives Des Maladies Du Coeur Et Des Vaisseaux
|September 28, 1998
Summary
Patients with coronary artery disease often have extracoronary atherosclerosis. The severity of coronary lesions strongly correlates with the presence and extent of peripheral arterial disease, increasing risks significantly.
Area of Science:
- Cardiovascular Medicine
- Vascular Biology
- Diagnostic Imaging
Background:
- Extracoronary atherosclerosis is common in patients with coronary artery disease.
- The relationship between coronary artery disease severity and peripheral atherosclerosis requires further investigation.
Purpose of the Study:
- To assess the prevalence and severity of extracoronary atherosclerosis in patients undergoing coronary angiography.
- To correlate extracoronary atherosclerosis with the presence and severity of coronary artery disease.
Main Methods:
- Ultrasonography was used to evaluate peripheral arterial disease in 728 patients with a history of coronary disease.
- Patients were categorized into three groups based on coronary angiography findings: no lesions, mild stenosis, and severe stenosis.
Main Results:
- A strong correlation was observed between coronary artery disease severity and peripheral arterial disease.
- Peripheral atherosclerosis prevalence increased from 45% in patients without coronary lesions to 88% in those with triple-vessel disease.
- Aortic aneurysms and simultaneous disease in three peripheral territories were more frequent in patients with severe coronary artery disease.
Conclusions:
- The prevalence and severity of peripheral atherosclerosis are closely linked to the presence, severity, and extent of coronary artery lesions.
- Patients with coronary artery disease have an increased risk of peripheral arterial disease, escalating with coronary disease severity.
- Ultrasonographic assessment of peripheral atherosclerosis is valuable in patients with known coronary artery disease.
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