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[Eukaryotic DNA topoisomerase and in vitro recombination between circular supercoiled plasmid DNA's in an in vitro
M V Glazkov1, Meshcheriakova YuA
1Vavilov Institute of General Genetics, Russian Academy of Sciences, Russia.
Genetika
|September 28, 1998
Abstract:
Eukaryotic DNA topoisomerase II was shown to catalyze recombination between circular supercoiled plasmid DNAs in vitro. The results obtained are discussed with regard to the organization of eukaryotic chromosomes in the form of topologically independent domains (loops).