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Folding motifs induced and stabilized by distinct cystine frameworks

H Tamaoki1, R Miura, M Kusunoki

  • 1Department of Biochemistry, Kumamoto University School of Medicine, Japan.

Protein Engineering
|September 28, 1998
PubMed
Summary

A conserved cystine framework, Cys-(X)1-Cys/Cys-(X)3-Cys, stabilizes a unique alpha-helix (CSH) motif in bioactive peptides and proteins. This structural element is crucial for protein folding and function across various biological systems.

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