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The Cooperative Groups: past and future

R L Comis1

  • 1Eastern Cooperative Oncology Group, Allegheny Cancer Center, Pittsburgh, PA, USA. COMIS@auhs.edu

Cancer Chemotherapy and Pharmacology
|September 28, 1998
PubMed
Summary

The National Cancer Institute (NCI) Cooperative Groups are adapting to shrinking funds and a changing healthcare landscape. They are implementing new strategies to enhance industry partnerships, international collaboration, and health outcomes research to maintain leadership in cancer clinical trials.

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Area of Science:

  • Oncology
  • Clinical Trials
  • Health Services Research

Background:

  • The National Cancer Institute (NCI) Cooperative Groups have a long history of conducting cancer clinical trials.
  • Current challenges include shrinking government funding and evolving healthcare environments in the USA.
  • There is a need for Cooperative Groups to adapt their operational mechanisms to maintain leadership in cancer research.

Purpose of the Study:

  • To outline necessary adjustments for NCI Cooperative Groups to sustain their leadership in cancer clinical trials.
  • To propose new approaches addressing operational inefficiencies, funding shortfalls, and the need for enhanced collaboration.
  • To integrate health outcomes and economic measures into clinical trial protocols.

Main Methods:

  • Discussion and strategic planning among Cooperative Group leaders.
  • Focus on establishing improved industry contracts and fostering international cooperation.
  • Emphasis on greater involvement of third-party payers and integration of economic measures.

Main Results:

  • Cooperative Groups are developing new strategies to address identified deficiencies.
  • Proposed changes aim to enhance efficiency in executing large phase III studies.
  • New approaches will complement existing NCI structures while respecting group independence.

Conclusions:

  • NCI Cooperative Groups are implementing changes to ensure continued leadership in cancer clinical trials.
  • These adjustments are expected to benefit patients, healthcare professionals, and the healthcare industry.
  • The goal is to remain at the forefront of cancer research and treatment evaluation into the 21st century.

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