Related Experiment Video
Updated: Aug 14, 2026

Use of Electromagnetic Navigational Transthoracic Needle Aspiration (E-TTNA) for Sampling of Lung Nodules
Published on: May 23, 2015
Characteristics of regions suspicious for pulmonary nodules at chest radiography
J A Drayer1, N F Vittitoe, R Vargas-Voracek
1School of Medicine, Duke University, Durham, NC, USA.
Rationale And Objectives:
This study was performed to determine physical characteristics of areas on chest radiographs that are suspicious but not definitive for the presence of a pulmonary nodule and the characteristics of areas that contain an obvious nodule.
Materials And Methods:
Two groups of patients were identified: those who had an area at plain radiography that was suspicious for a pulmonary nodule and underwent fluoroscopy for further evaluation (138 patients, 142 areas) and those who had an obvious nodule at plain radiography who underwent computed tomography for further evaluation (72 patients, 97 areas). The measured characteristics of the region of interest included size, circularity, compactness, contrast, and location.
Results:
A comparison of the data show that while there was some difference between these groups of patients with regard to location of the nodules, there were essentially no differences with regard to size, circularity, compactness, and contrast of the regions of interest.
Conclusion:
Size, circularity, compactness, contrast, and location are not sufficient to distinguish pulmonary nodules from other suspicious regions on the chest radiograph.
Related Concept Videos
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration can...
Respiratory System Abnormal Finding I: Inspection and Percussion
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
Radiological Investigation I: X-ray and CT
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

