Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biliary tract neoplasms

D N Sharma1, S Chawla, M Gairola

  • 1Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.

Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation
|September 30, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and Determinants of Female Sexual Dysfunction, and Its Association With Neurotrophic Biomarkers in Gynaecological Cancer Survivors: A Cross-Sectional Study.

Cancer control : journal of the Moffitt Cancer Center·2026
Same author

Outcomes of Stage IVA Cervical Cancer Treated with Radiation Therapy: A Systematic Review and Meta-Analysis.

International journal of radiation oncology, biology, physics·2026
Same author

Lymph Node Ratio as an Independent Prognostic Factor in Breast Cancer: A Retrospective Study of 4060 Patients Undergoing Axillary Lymph Node Dissection.

Clinical breast cancer·2026
Same author

Non-coding RNA regulation of the radiation-induced DNA damage response and its translational relevance.

Discover oncology·2026
Same author

A case series and literature review on extramedullary hematopoiesis in patients with thalassemia treated with conformal external beam radiation treatment.

Radiation oncology (London, England)·2025
Same author

Neoadjuvant Chemotherapy Followed by Surgery-A Promising Strategy to Reduce Morbidity in Locally Advanced Tongue Cancer.

Head & neck·2025

Biliary neoplasms are most common in adults aged 40-60. Most patients present with advanced disease, requiring palliative care, with limited survival rates even after curative treatment.

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Biliary neoplasms represent a significant clinical challenge.
  • Early diagnosis and effective treatment strategies are crucial for improving patient outcomes.

Purpose of the Study:

  • To analyze the clinical characteristics, treatment patterns, and survival outcomes of patients diagnosed with biliary neoplasms.
  • To evaluate the proportion of patients eligible for curative versus palliative treatment.

Main Methods:

  • Retrospective analysis of complete medical records for 124 patients with biliary neoplasms from January 1993 to December 1995.
  • Data collected included patient demographics, histopathology, presenting symptoms, associated conditions, disease stage, treatment received, and survival.
  • Patients were categorized based on eligibility for curative or palliative treatment.

Related Experiment Videos

Main Results:

  • The study included 124 patients (38 males, 86 females), with a median age of 54 years. Adenocarcinoma was the most common histopathological type (59%).
  • Common presenting symptoms included pain (119 patients) and jaundice (54 patients). Fifty-six patients had associated gallstones.
  • Ninety patients (72.5%) presented with metastatic disease, and 110 patients (88.7%) had advanced, inoperable disease, necessitating palliative treatment. Only 14 patients (12%) were considered for curative treatment.
  • Among the 14 patients receiving curative treatment (surgery, radiotherapy, chemotherapy), survival ranged from 2 to 44 months, with a mean survival of 16 months. Follow-up was noted as poor.

Conclusions:

  • Biliary neoplasms predominantly affect individuals aged 40-60 and frequently present at advanced stages, limiting curative treatment options.
  • Palliative care is the primary approach for the majority of patients due to inoperable disease at presentation.
  • Survival outcomes for patients undergoing curative treatment remain limited, highlighting the need for improved early detection and novel therapeutic strategies.