Related Experiment Video
Updated: Jul 23, 2026
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
[The results of prostatic adenomectomy in patients with severe concomitant diseases]
Insights
Prostate adenomectomy shows good long-term functional results and patient rehabilitation, even in elderly patients with comorbidities. The procedure demonstrates a low complication rate and manageable mortality in this complex surgical group.
Area of Science:
- Urology
- Geriatric Medicine
- Surgical Oncology
Context:
- Prostate adenomectomy is a common surgical procedure for benign prostatic hyperplasia.
- Elderly patients often present with multiple comorbidities, increasing surgical risk.
- Understanding outcomes in this population is crucial for clinical decision-making.
Purpose:
- To evaluate the immediate and long-term outcomes of prostate adenomectomy.
- To assess the safety and efficacy of the procedure in elderly patients and those with concomitant diseases.
- To analyze the functional results and rehabilitation rates post-surgery.
Summary:
- A study of 1549 patients undergoing prostate adenomectomy, including 322 elderly individuals, revealed high rates of concomitant diseases (96.8%).
- Transvesical adenomectomy with specific hemostasis techniques resulted in an uncomplicated postoperative period for 89.5% of patients.
- Postoperative mortality was 3.2% in patients with comorbidities, with cardiovascular and cerebrovascular conditions being leading causes.
- Long-term follow-up (6 months to 11 years) showed good functional results in 91.2% of patients, with significant medical and social rehabilitation observed.
Impact:
- This study highlights the feasibility and positive long-term outcomes of prostate adenomectomy in a complex patient cohort.
- Findings support the consideration of prostate adenomectomy for elderly patients and those with significant comorbidities.
- The data provides valuable insights into managing surgical risks and optimizing patient recovery in this demographic.
Abstract:
Immediate and long-term results of prostate adenomectomy were studied in 1549 patients, 322 of whom being of old age. In 1499 (96.8%) patients concomitant diseases were revealed: ischemic heart disease (934 patients), cardiosclerosis after 1-3 myocardial infarction (185), hemiparesis after acute cerebrovascular disturbances (74), diabetes mellitus (88), chronic lymphoid leukemia (5), cirrhosis of the liver (15), cancer (22) and true diverticula (15) of the urine bladder, drug-related polyallergy (16). 628 patients were radically operated in conditions of circulatory insufficiency of stage I-II. In 631 (40.7%) patients surgical intervention was carried out as urgent because of acute dysuria (hampering of urination) or to bleeding from tumor. Transvesical adenomectomy was carried out with hemostasis by 2 semipouch string removable sutures. In 89.5% of patients uncomplicated course of postoperative period was observed. Postoperative lethality in patients with concomitant diseases made up 3.2%. Causes of death were postinfarction cardiosclerosis (6.5%), after-effect of cerebrovascular stroke (5.4%), diabetes mellitus (5.7%), cirrhosis of the liver (6.7%). 6 months to 11 years after the operation 91.2% of the patients achieved good follow-up functional results of surgical treatment, in majority of the patients medical and social rehabilitation was observed.
