Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Peripapillary atrophy in normal and primary open-angle glaucoma

K B Uhm¹, D Y Lee, J T Kim

¹Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.

Korean Journal of Ophthalmology : KJO

|October 1, 1998

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Integration of transcriptomic data identifies CD163 as a key link between chronic rhinosinusitis with nasal polyps and COVID-19.

Rhinology·2026

Same author

[Intraluminal intervention therapy for pulmonary vascular stenosis caused by fibrous mediastinitis:report of two cases].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2025

Same author

Modulatory Effect of Blood LDL Cholesterol on the Association between Cerebral Aβ and Tau Deposition in Older Adults.

The journal of prevention of Alzheimer's disease·2024

Same author

[Clinical features of pulmonary hypertension in lymphangioleiomyomatosis].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2024

Same author

Comparison of in-shoe plantar pressure between Korean combat boots and running shoes.

BMJ military health·2024

Same author

Diagnosis of osteochondral lesions of the talus on Dual-layer spectral detector CT arthrography: clinical feasibility of virtual noncontrast images.

Clinical radiology·2024

Measuring peripapillary atrophy helps diagnose and monitor glaucoma. Increased atrophy correlates with optic nerve damage and visual field loss in glaucoma patients.

Area of Science:

Ophthalmology
Glaucoma Research
Optic Nerve Imaging

Background:

Glaucoma is a leading cause of irreversible blindness.
Peripapillary atrophy (PPA) is a known feature in glaucoma.
The diagnostic and prognostic value of PPA requires further investigation.

Purpose of the Study:

To assess the utility of peripapillary atrophy measurement in glaucoma diagnosis and follow-up.
To evaluate the relationship between peripapillary atrophy and structural/functional optic nerve damage in glaucoma.

Main Methods:

Magnification-corrected morphometry of fundus photographs.
Automated static threshold perimetry.
Study included 234 eyes with primary open-angle glaucoma and 86 normal subjects.

Related Experiment Videos

Main Results:

Peripapillary atrophy (zones alpha and beta) was significantly larger and more extensive in glaucoma patients.
Zone beta frequency increased with glaucoma stage.
PPA extent correlated significantly with structural damage (rim/disc ratio, cup area) and visual field defects (mean deviation).

Conclusions:

Increased peripapillary atrophy is linked to the severity of glaucomatous optic nerve damage.
Peripapillary atrophy measurement is valuable for diagnosing and tracking glaucoma progression.