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Related Experiment Videos

Hemispheric control of motor function: a whole brain echo planar fMRI study

V S Mattay1, J H Callicott, A Bertolino

  • 1Clinical Brain Disorders Branch, NIMH, NIH, Bethesda, MD 20892, USA.

Psychiatry Research
|October 1, 1998
PubMed
Summary

Non-dominant hand movements recruit more ipsilateral motor cortex areas, suggesting greater cortical involvement due to task complexity or unfamiliarity rather than just left hemispheric control. This highlights individual brain activity nuances.

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Area of Science:

  • Neuroscience
  • Motor Control
  • Brain Imaging

Background:

  • Understanding hemispheric control of motor function is crucial.
  • The role of ipsilateral motor cortex recruitment during non-dominant hand movements is debated.
  • Task complexity and familiarity may influence motor cortex activation patterns.

Purpose of the Study:

  • To investigate whether ipsilateral motor cortex activation during non-dominant hand movements reflects left hemispheric control or task demands.
  • To differentiate between motor control and task complexity/unfamiliarity as drivers of ipsilateral activation.
  • To explore the impact of dominant vs. non-dominant hand use on motor cortex recruitment.

Main Methods:

  • Blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) was used.

Related Experiment Videos

  • Participants performed sequential (SM) and random (RM) finger movement tasks with their dominant (right) and non-dominant (left) hands.
  • Analysis included both single-subject and group-level fMRI data.

    • Main Results:

    • Predominant activation was observed in contralateral motor areas and ipsilateral cerebellum.
    • Ipsilateral motor cortex activation was more extensive and frequent during non-dominant hand SM tasks and dominant hand RM tasks.
    • Group analysis confirmed ipsilateral activation in sensorimotor and premotor areas for non-dominant SM and dominant RM tasks.
    • Individual subject analysis revealed patterns potentially obscured by group averaging.

    Conclusions:

    • Non-dominant hand movements, potentially less automatic, require increased cortical activity.
    • Greater recruitment of ipsilateral cortical motor areas and striatum is associated with less automatic movements.
    • Task complexity and unfamiliarity, rather than solely hemispheric control, appear to drive ipsilateral motor cortex activation.