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A safe, simple method for preparing heat-damaged red cells for diagnosing splenic infarct or trauma
1Department of Nuclear Medicine, Royal North Shore Hospital, Sydney, Australia.
Journal of Nuclear Medicine Technology
|October 2, 1998
Abstract
Objective:
The purpose of this study was to demonstrate a fast, safe and simple method for preparing heat-damaged red blood cells.
Methods:
Patient blood was radiolabeled using the Ultra-Tag RBC kit and then heated to 49.5 degrees C for 20 min. The reaction vial was cooled in ice water for 1 min and the required activity was administered to the patient. The patient was imaged 60 min postinjection.
Results:
High-quality planar and SPECT images of the spleen were obtained with low background activity noted. Radiolabeling efficiency was greater than 95%.
Conclusion:
The method was safe and simple to perform. High-quality images of the spleen were obtained.