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Updated: Aug 5, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
[Electro-cardiographic correlation in the diagnosis of left ventricular hypertrophy]
H Domingos1, J C Luzio, G N de Leles
1Universidade Federal de Mato Grosso do Sul-Campo Grande.
Insights
Electrocardiogram (ECG) criteria for diagnosing left ventricular hypertrophy (LVH) in hypertensive patients showed low accuracy. Even when combined, these ECG methods are insufficient for reliable LVH diagnosis.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- Left ventricular hypertrophy (LVH) is a common condition in hypertensive patients.
- Accurate diagnosis of LVH is crucial for managing cardiovascular risk.
Purpose of the Study:
- To evaluate the diagnostic efficacy of four common electrocardiographic (ECG) criteria for LVH.
- Comparison of Sokolov, Gubner, Cornell, and Romhilt indexes in hypertensive individuals.
Main Methods:
- Analyzed ECGs of 30 ambulatory hypertensive patients.
- Assessed Sokolov, Gubner, Cornell, and Romhilt indexes against echocardiography as the gold standard for LVH.
- Calculated sensitivity, specificity, and diagnostic accuracy.
Main Results:
- The Sokolov index demonstrated the highest individual accuracy (50%), sensitivity (40%), and specificity (100%).
- Combined ECG criteria improved sensitivity to 52% and accuracy to 57% but remained suboptimal.
- Gubner, Romhilt, and Cornell indexes showed lower performance individually.
Conclusions:
- The evaluated ECG criteria are not sufficiently accurate for diagnosing LVH in hypertensive patients.
- Given the high prevalence of LVH, alternative diagnostic methods are recommended.
- Further research into more precise diagnostic tools for LVH is warranted.
Purpose:
To compare the efficacy of four electrocardiographic criteria: Sokolov, Gubner, Cornell and Romhilt indexes, in the diagnosis of left ventricular hypertrophy (LVH) in hypertensive patients.
Methods:
LVH was analyzed in the electrocardiogram of 30 ambulatory patients presenting with systemic arterial hypertension, classified as mild, moderate and severe, according to the following indexes: Sokolov > or = 35 mm, Gubner > or = 22 mm, Romhilt > or = 5 points and Cornell > or = 20 mm for women and 28 mm for men. Sensitivity, specificity, diagnostic accuracy and other diagnostic variables were determined Mass index of the left ventricle, > or = 98 g/m2 for women and > or = 120 g/m2 for men, obtained by echocardiography, was considered the gold standard for the diagnosis of LVH.
Results:
When electrocardiographic criteria were considered separately, the Sokolov index showed the highest accuracy, with a sensitivity of 40%, diagnostic accuracy of 50% and specificity of 100%; the second most accurate index was Gubner, and Romhilt and Cornell indexes followed. When at least one of the indexes was positive, the sensitivity was 52% and diagnostic accuracy was 57%.
Conclusion:
The four electrocardiographic indexes were not diagnostic of LVH, when analyzed either separately or together. Considering the high prevalence of this pathological condition, we conclude that a more accurate diagnostic method should be used in this diagnosis.
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