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[Occult breast cancer]

D Vasile1, R Palade, D Voiculescu

  • 1Clinica Chirurgie I, Spitalul Universitar Bucureşti.

Chirurgia (Bucharest, Romania : 1990)
|October 2, 1998
PubMed
Summary
This summary is machine-generated.

Breast cancer presenting as an axillary mass (BCAM) is rare, accounting for 0.9% of cases. This presentation often leads to delayed diagnosis and poor prognosis, with only 28% of patients surviving five years.

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Area of Science:

  • Oncology
  • Surgical Pathology

Context:

  • Breast cancer commonly presents as a palpable breast mass.
  • Axillary lymph node involvement is a key indicator of breast cancer metastasis.

Purpose:

  • To analyze the clinical presentation, diagnosis, treatment, and outcomes of breast cancer presenting as an axillary mass (BCAM).

Summary:

  • Seven cases of BCAM were identified over 20 years (0.9% of total breast cancer cases).
  • The primary clinical sign was axillary lymphadenopathy, with diagnosis confirmed by pathological examination of lymph nodes.
  • Mammography revealed small tumors (<1 cm) in 3 cases. Staging varied from II to IV.
  • All patients underwent surgery (mastectomy or modified radical mastectomy), followed by chemotherapy and radiotherapy.
  • The 5-year survival rate was low, with only 2 out of 7 patients surviving.

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Impact:

  • Highlights the diagnostic challenges and poor prognosis associated with breast cancer presenting solely as an axillary mass.
  • Emphasizes the need for thorough investigation of axillary lymphadenopathy, even in the absence of a primary breast tumor.
  • Suggests that BCAM may represent a more advanced stage of breast cancer at diagnosis.