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[Feto-maternal transfusion following cordocentesis]

J Sikovanyecz¹, T Nyári, M Faragó

¹Szent-Györgyi Albert Orvostudományi Egyetem, Szeged, Szülészeti és Nögyógyászati Klinika.

|October 2, 1998

Summary

Feto-maternal transfusion, a potential complication of cordocentesis, was studied in 199 women. Increased transfusion correlated with longer procedure times and bleeding, suggesting it indicates procedural difficulty.

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Area of Science:

Obstetrics and Gynecology
Fetal Medicine
Maternal-Fetal Medicine

Context:

Invasive intrauterine diagnostic procedures, such as cordocentesis, can lead to feto-maternal transfusion.
Understanding the factors influencing feto-maternal transfusion is crucial for improving procedural safety.

Purpose:

To investigate the incidence and influencing factors of feto-maternal transfusion following fetal umbilical cord blood sampling (cordocentesis).

Summary:

This study analyzed 199 women undergoing cordocentesis for fetal karyotyping between 15-26 weeks gestation.
Feto-maternal transfusion occurred in 36.7% of cases, with an average transfusion of 0.045 ml.
Positive correlations were found between transfusion, bleeding time, and procedure duration. Negative correlation was observed with the volume of fetal blood sampled.

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Transfusion rates varied based on puncture site, being lower at the cord insertion and higher with transplacental approaches.

Impact:

The findings suggest that feto-maternal transfusion serves as an indicator of procedural difficulty during cordocentesis.
Identifying factors associated with increased transfusion can help refine techniques and minimize risks during invasive fetal procedures.