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Extramedullary hematopoietic effusions
A García-Riego1, C Cuiñas, J J Vilanova
1Department of Anatomic Pathology, Hospital de Cruces, Vizcaya, Spain.
Objective:
To investigate the frequency and diagnostic implications of extramedullary hematopoietic effusions.
Study Design:
Smears of the effusions diagnosed cytologically as myeloid metaplasia or extramedullary hematopoiesis and their clinical records were reviewed and compared with the histologic diagnoses.
Results:
There were 7 pleural and 1 peritoneal effusion from 5 patients out of 20,793 pericardial, peritoneal and pleural effusions studied during a period of 21 years.
Conclusion:
When compensatory responses can be ruled out, the diagnosis of extramedullary hematopoietic effusion points toward replacement of the bone marrow by a metastatic process. The first primary to consider in males is lung carcinoma.