Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Development of Bacillus thuringiensis fermentation and process control from a practical perspective

X M Yang1, S S Wang

  • 1Merck & Co., Inc., P.O. Box 4, WP60T-5, West Point, PA 19486, USA.

Biotechnology and Applied Biochemistry
|October 2, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Effects of different ages and body mass index on embryo development time kinetic parameters and embryo development potential].

Zhonghua yi xue za zhi·2020
Same author

[Epidemic characteristics and trend analysis of the COVID-19 in Hubei province].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2020
Same author

[Characteristics of rare diseases in Zhejiang province, 2007-2017].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2020
Same author

[Epidemiological investigation of a family clustering of COVID-19].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2020
Same author

[Interaction of health literacy and second-hand smoke exposure on psychopathological symptoms of middle school students].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]·2020
Same author

[Prediction of clinical outcomes of patients with surplus cleavage-stage embryos for blastocyst culture after D3 embryo transfer].

Zhonghua yi xue za zhi·2019
Same journal

Development and Validation of an ELISA Method for Quantification of HuB01 in Fermentation Products.

Biotechnology and applied biochemistry·2026
Same journal

Optimization and Characterization of Poly-γ-Glutamic Acid Production From a Locally Isolated Bacillus cereus ARM24.

Biotechnology and applied biochemistry·2026
Same journal

Isolation and Characterization of a Novel Microbacterium takaoensis Lipase for Nutritional and Textural Improvement of Pizza Dough.

Biotechnology and applied biochemistry·2026
Same journal

Targeting Amastigote and Trypomastigote Phases: Multi-Epitope Vaccine Strategy Against Trypanosoma cruzi.

Biotechnology and applied biochemistry·2026
Same journal

Novel Inhibitors Targeting Class B1 Metallo-β-Lactamases in Carbapenem-Resistant Acinetobacter baumannii.

Biotechnology and applied biochemistry·2026
Same journal

Formulation of PLA/Chitosan Copolymeric Nanocarriers Enhanced the Sustained and Targeted Drug Delivery of Cinnamic Acid: In Vitro Drug Optimization and In Vivo Biodistribution in Rat Model.

Biotechnology and applied biochemistry·2026
See all related articles

Bacillus thuringiensis (Bt) biopesticide production needs higher yields. Future research should focus on optimizing toxin protein production and genetically engineered strains for cost-effective biological control.

Area of Science:

  • Microbiology
  • Biotechnology
  • Bioprocess Engineering

Background:

  • Bacillus thuringiensis (Bt) is a key biopesticide producer.
  • High yield in Bt fermentation is crucial for cost-competitiveness against chemical pesticides.
  • Current research focuses on spore count, with less emphasis on toxin protein yield.

Purpose of the Study:

  • To review the development of Bacillus thuringiensis (Bt) fermentation processes.
  • To identify future research opportunities and potential improvements in Bt biopesticide production.
  • To highlight the need for process development in genetically engineered Bt strains.

Main Methods:

  • Literature review of Bt fermentation physiology.
  • Analysis of Bt growth dynamics.

Related Experiment Videos

  • Examination of high-yield process control strategies.

    • Main Results:

    • Many studies prioritize improving spore count over toxin protein yield.
    • There is a lack of process research specifically targeting enhanced toxin protein yield.
    • Genetically engineered Bt strains offer significant opportunities for improved yields.

    Conclusions:

    • Further research is needed to optimize toxin protein production in Bacillus thuringiensis (Bt) fermentation.
    • Process development for genetically modified Bt strains expressing multiple toxins presents a promising avenue.
    • Enhancing Bt fermentation yields is critical for the biopesticide industry's market competitiveness.