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Updated: Aug 13, 2026

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
In vitro activities of 15 antimicrobial agents against clinical isolates of South African enterococci
M C Struwig1, P L Botha, L J Chalkley
1Department of Medical Microbiology, University of the Orange Free State, Bloemfontein 9300, South Africa. GNMBDS@med.uovs.ac.za
Abstract:
The activities of a panel of currently available antibiotics and the investigational agents LY 333328, linezolid, CL 331,002, CL 329,998, moxifloxacin (BAY 12-8039), trovafloxacin, and quinupristin-dalfopristin against 274 clinical isolates of enterococci were determined. No vancomycin resistance or beta-lactamase production was observed. Except for 12 isolates (all non-Enterococcus faecalis) showing reduced susceptibility to quinupristin-dalfopristin (MIC, >/=4 microg/ml), the new agents exhibited promising in vitro antienterococcal activity.
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