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Respiratory responses to chemical stimulation of the parabrachial nuclear complex in the rabbit
D Mutolo1, F Bongianni, M Carfì
1Dipartimento di Scienze Fisiologiche, Università degli Studi di Firenze, Viale G.B. Morgagni 63, I-50134, Florence, Italy.
Brain Research
|October 3, 1998
Abstract:
The respiratory role of the parabrachial nuclear complex (PNC) was investigated in alpha-chloralose-urethane anesthetized, vagotomized, paralysed and artificially ventilated rabbits by means of unilateral microinjections (10-20 nl) of 20 mM dl-homocysteic acid. Chemical stimulation elicited three main types of site-specific respiratory effects: excitatory, apneustic and inhibitory responses. The results suggest that the PNC plays a complex role in the control of breathing.