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[Recent treatment modality for advanced head and neck carcinomas]
1Department of Otolaryngology, Yokohama City University School of Medicine, Japan.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|October 3, 1998
Summary
This review covers head and neck squamous cell carcinoma treatments, focusing on prognostic factors and advanced case management. It examines conventional, multidisciplinary, and emerging chemotherapy approaches for better outcomes.
Area of Science:
- Oncology
- Head and Neck Surgery
- Radiation Oncology
Context:
- Head and neck cancer predominantly presents as squamous cell carcinoma (approximately 90%).
- Current curative treatments involve radiotherapy and/or surgical resection.
- Advanced cases often require multidisciplinary approaches, including chemotherapy and immunotherapy, with limited success.
Purpose:
- To review treatment strategies for head and neck cancer.
- To analyze prognostic factors influencing treatment outcomes.
- To explore recent advancements in managing advanced head and neck carcinomas.
Summary:
- Histopathological analysis confirms squamous cell carcinoma as the primary type of head and neck cancer.
- Conventional treatments include radiotherapy and surgery; advanced cases utilize multidisciplinary strategies.
- Chemotherapy is being investigated in neoadjuvant, adjuvant, and concurrent chemoradiotherapy settings.
Impact:
- Provides insights into prognostic factors for head and neck cancer.
- Highlights current and developing treatment modalities for advanced disease.
- Informs clinical decision-making for head and neck squamous cell carcinoma management.