[What is bright on T1 MRI scans?]
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Updated: Oct 28, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
E de Kerviler1, C A Cuenod, O Clément
1Service de Radiologie, Hôpital Saint-Louis, Paris.
Abstract:
The list of entities associated with a high signal intensity on T1-weighted images is extensive and classically includes fat, proteins, hemorrhage, melanin and gadolinium. However, additional entities may be responsible for abnormally high signal intensity on T1-weighted images. These include ion deposition in metabolic disorders, free radicals, increased proton density, flow phenomena, some artifacts, and new contrast agents. The aim of this article is to display both the common and uncommon causes for a high T1 signal intensity and to discuss the underlying mechanisms or attributable pathophysiology for this phenomenon.
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