[Acquired lesions of the corpus callosum]

Acquired lesions of the corpus callosum may be related to tumoral, vascular, traumatic or degenerative disorders and, one must not forget, can result from surgical access. Currently, the quality of neuroimaging enables a validation or precision of anatomoclinical, neuropsychological and neurophysiological correlations established from experimental and/or autopsy data. However the "specific" signs of acquired lesions of the corpus callosum are often quite complex and may be readily overlooked or masked within a heterogeneous clinical presentation due to more or less important associated lesions of neighboring structures. Therapeutic management (tumors, arteriovenous malformations, cavernomas) depend on the nature and the extent of the lesion more than the functional nature of this inter-hemispheric commissure with an exceptional functional plasticity, particularly when the lesion is limited.