Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diabetes mellitus and left ventricular function

S S Ahmed, T J Regan

    Comprehensive Therapy
    |November 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Chronic diabetes mellitus can impair heart function by affecting the heart muscle itself, independent of blood vessel issues. This preclinical abnormality may lead to heart failure if underlying heart muscle disease worsens or other conditions arise.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Use of preoperative opioids increases duration of hospital stay following elective lower limb arthroplasty. - A snapshot of UK practice.

    Journal of orthopaedics·2020
    Same author

    Prosthetic joint infection.

    Bone & joint research·2019
    Same author

    The effects of hypogonadism on quality of life in survivors of germ cell tumors treated with surgery alone versus surgery plus platinum-based chemotherapy.

    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2019
    Same author

    Evaluation of a human in vitro skin test for predicting drug hypersensitivity reactions.

    Toxicology and applied pharmacology·2019
    Same author

    Three-layer reconstruction of lower third nasal defects using forehead flap, reversed nasolabial flap, and auricular cartilage.

    International journal of oral and maxillofacial surgery·2016
    Same author

    Bilateral Transverse Facial Cleft as an Isolated and Asyndromic Deformity.

    International journal of clinical pediatric dentistry·2016
    Same journal

    Heparin-induced thrombocytopenia and thrombosis.

    Comprehensive therapy·2011
    Same journal

    Antiplatelet therapy in cardiovascular disease.

    Comprehensive therapy·2011
    Same journal

    Genetics of cardiovascular disease.

    Comprehensive therapy·2011
    Same journal

    Septic renal vein thrombosis complicated by septic pulmonary embolism.

    Comprehensive therapy·2011
    Same journal

    Gout and hyperuricemia.

    Comprehensive therapy·2011
    Same journal

    Problems with computerized health records.

    Comprehensive therapy·2011
    See all related articles

    Area of Science:

    • Cardiology
    • Endocrinology
    • Pathology

    Background:

    • Chronic diabetes mellitus is known to affect cardiovascular health.
    • Existing research suggests potential cardiac alterations in diabetic patients.

    Purpose of the Study:

    • To investigate the impact of chronic diabetes mellitus on left ventricular function.
    • To explore the role of myocardial interstitial changes in preclinical diabetic cardiomyopathy.

    Main Methods:

    • Analysis of morphologic data from human and canine diabetic models.
    • Assessment of left ventricular function independent of vascular effects.

    Main Results:

    • Diabetes mellitus can alter left ventricular function independently of vascular complications.

    Related Experiment Videos

  • Myocardial interstitial alterations are implicated as a basis for this preclinical abnormality.
  • The observed functional abnormality is independent of diabetes duration, treatment, sex, or age.

    • Conclusions:

    • Diabetic cardiomyopathy may stem from intrinsic myocardial changes.
    • Progression to clinical heart failure could be influenced by myocardial pathophysiology and comorbid conditions like hypertension and obesity.