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[Renal candidiasis following treatment of infantile osteomyelitis]
1Semmelweis Orvostudományi Egyetem, Budapest.
Insights
Systemic candidiasis is rare in infants, but this case highlights a preterm infant developing kidney complications including obstruction due to fungal infection. Treatment required both antifungal medication and surgery to remove the fungal mass.
Area of Science:
- Pediatric Nephrology
- Mycology
- Infectious Diseases
Background:
- Systemic candidiasis is uncommon in neonates and young infants.
- Renal involvement in infant candidiasis presents diagnostic and therapeutic challenges.
Observation:
- A preterm infant receiving broad-spectrum antibiotics for osteomyelitis developed a systemic fungal infection.
- The infection led to bilateral pyelonephritis and pyeloureteral obstruction.
Findings:
- The mycotic infection resulted in the formation of a fungal bezoar within the renal system.
- Successful management necessitated a combination of systemic antifungal therapy and surgical intervention.
Implications:
- This case underscores the importance of considering fungal infections in infants with unexplained renal complications, especially those on prolonged antibiotics.
- Prompt diagnosis and multimodal treatment (antifungal and surgical) are crucial for favorable outcomes in infant systemic candidiasis with renal obstruction.
Abstract:
Systemic candidiasis with renal complications is a rather rare phenomenon in young infants. Authors report on a 4.5 month-old baby (preterm) who, during an antibiotic therapy of wide spectrum--because of osteomyelitis--acquired a mycotic infection causing bilateral pyelon and pyeloureteral obstruction. In addition to systemic antimycotic therapy surgical intervention was needed to eliminate the mycotic bezoar.