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Interleukin 2 receptor regulation and IL-2 function in the human infant

H Zola1, J Ridings, S Elliott

  • 1Child Health Research Institute, Adelaide, Australia. hzola@medicine.adelaide.edu.au

Human Immunology
|October 3, 1998
PubMed
Summary

Neonatal and infant lymphocytes have lower IL-2 receptor expression than adults, with reduced mRNA levels. However, these cells can up-regulate receptors and respond to IL-2, suggesting potential in vivo dampening of the IL-2 system in infancy.

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