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[Adoption and chronic hepatitis B carrier state]
J J Choulot1, S Mechain, J Saint Martin
1Service de pédiatrie, centre hospitalier général de Pau, France.
Summary
International adoption can expose children to chronic hepatitis B virus (HBV) infection. Early screening and preventive measures are crucial for adopted children
Area of Science:
- Pediatric Infectious Diseases
- Hepatology
- Public Health
Context:
- International adoption has increased in France due to a shortage of adoptable children domestically.
- Internationally adopted children often present with significant health issues upon arrival.
- Hepatitis B virus (HBV) infection is a growing concern among this population.
Purpose:
- To investigate the prevalence of hepatitis B virus (HBV) infection in internationally adopted children.
- To identify risk factors and co-infections associated with HBV in adopted children.
- To assess the health status of internationally adopted children, focusing on HBV.
Summary:
- A study of 60 internationally adopted children revealed that 6 (10%) were chronic HBV carriers.
- Of the carriers, 5 had detectable HBV DNA, and one was co-infected with the delta virus.
- Elevated aminotransferase levels were observed in half of the HBV-positive children.
Impact:
- Highlights the risk of chronic HBV infection in internationally adopted children, particularly those from high-prevalence regions or with extended stays in Eastern European institutions.
- Emphasizes the potential for transmission within families and educational settings, necessitating prompt screening and vaccination.
- Underscores the importance of implementing preventive strategies to mitigate the public health impact of HBV in this vulnerable group.