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A family study of anterior mitral leaflet thickness and mitral valve prolapse
A Zuppiroli1, M J Roman, M O'Grady
1Department of Medicine, The New York Hospital-Cornell Medical Center, New York 10021, USA.
The American Journal of Cardiology
|October 7, 1998
Abstract:
To determine whether mitral valve prolapse (MVP) with or without mitral leaflet thickening (> or =5 mm) represents distinct heritable conditions, 13 patients with MVP with leaflet thickening and their relatives were compared with 67 patients with MVP with normal leaflets and their relatives. The 2 groups of relatives had similar mitral leaflet thicknesses and similar long-term outcome, arguing against the existence of a distinctive subtype of MVP characterized by increased mitral leaflet thickness.