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Relapsing cutaneous polyarteritis nodosa associated with streptococcal infections

M A Albornoz1, A V Benedetto, M Korman

  • 1Department of Internal Medicine, Mercy Catholic Medical Center, Darby, Pennsylvania, USA.

International Journal of Dermatology
|October 8, 1998
PubMed
Summary

This study documents a rare case of recurrent cutaneous polyarteritis nodosa in a female patient over 20 years. Each episode of this skin vasculitis appeared linked to prior streptococcal pharyngitis infections.

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Area of Science:

  • Rheumatology
  • Dermatology
  • Infectious Diseases

Background:

  • Polyarteritis nodosa (PAN) is a severe systemic vasculitis with high mortality.
  • Cutaneous polyarteritis nodosa (cPAN) is considered a less severe form, primarily affecting the skin.

Observation:

  • A unique case of a female patient experiencing recurrent cPAN from childhood to adulthood is presented.
  • The patient had multiple documented episodes of cPAN over two decades.

Findings:

  • Each cPAN episode was preceded by recurrent streptococcal pharyngitis.
  • Histopathologic skin changes and clinical presentation confirmed cPAN, with therapeutic management validating the diagnosis.

Implications:

  • This case highlights a potential long-term association between streptococcal infections and recurrent cPAN.

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  • Understanding such triggers is crucial for managing cPAN and preventing disease flares.