Related Experiment Video
Updated: Aug 19, 2026

Cholesterol Efflux Assay
Published on: March 6, 2012
Selective opportunistic screening for hypercholesterolemia in primary care practice
B Hutchison1, S Birch, C E Evans
1Department of Family Medicine, Centre for Health Economics and Policy Analysis, McMaster University, Hamilton, Ontario, Canada.
Objectives:
To assess the performance of selective opportunistic screening in a primary care group practice.
Design:
Cross-sectional survey of coronary heart disease risk factors and retrospective chart audit of cholesterol testing.
Setting:
Capitation-funded primary care group practice in Ontario, Canada.
Subjects:
7785 enrolled patients between the ages of 20 and 69 years.
Intervention:
Protocol-based selective opportunistic screening program for hypercholesterolemia of 45 months duration.
Main Outcome Measures:
Targeting (proportion of screening tests that were appropriate), coverage (proportion of those meeting screening criteria who had a screening test performed), over-screening (proportion of those not meeting screening criteria who had a screening test performed), and screening ratio (likelihood that a screening test was performed on an individual who met screening criteria rather than one who failed to meet screening criteria).
Results:
64.7% of patients tested met the practice criteria for screening. 37.7% of patients who met the practice screening criteria were tested and 24.9% of those not meeting practice screening criteria had a cholesterol test performed. The screening ratio was 1.52.
Conclusion:
Our findings bring into question the effectiveness of opportunistic approaches to preventive care.
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