Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fast fluid-attenuated inversion-recovery imaging: first experience with a 3D version in epilepsy

U C Wieshmann1, G J Barker, M R Symms

  • 1Epilepsy Research Group, Institute of Neurology, London, UK. uwiesh@ion.ucl.ac.uk

Neuroradiology
|October 8, 1998
PubMed
Summary

A new 3D fast FLAIR MRI technique offers improved lesion detection in epilepsy patients. This advanced imaging method, with 1.5 mm slice thickness, excels at visualizing low-grade tumors compared to standard sequences.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Results from the T2K Experiment on Neutrino Mixing Including a New Far Detector μ-like Sample.

Physical review letters·2026
Same author

First Differential Measurement of the Single π^{+} Production Cross Section in Neutrino Neutral-Current Scattering.

Physical review letters·2025
Same author

First Measurement of the Electron-Neutrino Charged-Current Pion Production Cross Section on Carbon with the T2K Near Detector.

Physical review letters·2025
Same author

First Joint Oscillation Analysis of Super-Kamiokande Atmospheric and T2K Accelerator Neutrino Data.

Physical review letters·2025
Same author

Measurements of neutrino oscillation parameters from the T2K experiment using <math><mrow><mn>3.6</mn><mo>×</mo><msup><mn>10</mn><mn>21</mn></msup></mrow></math> protons on target.

The European physical journal. C, Particles and fields·2023
Same author

Parker Solar Probe Observations of Solar Wind Energetic Proton Beams Produced by Magnetic Reconnection in the Near-Sun Heliospheric Current Sheet.

Geophysical research letters·2022

Area of Science:

  • Radiology
  • Medical Imaging
  • Neurology

Background:

  • Epilepsy diagnosis often relies on detailed neuroimaging.
  • Conventional MRI sequences may have limitations in detecting subtle lesions.

Purpose of the Study:

  • To evaluate the utility of a novel 3D fast FLAIR MRI sequence in patients with lesional epilepsy.
  • To compare the diagnostic performance of 3D fast FLAIR with 2D fast FLAIR and 3D spoiled GRASS sequences.

Main Methods:

  • Development of a 3D fast FLAIR MRI technique with 1.5 mm slice thickness.
  • Comparison of 3D fast FLAIR, 2D fast FLAIR (5 mm slice thickness), and 3D spoiled GRASS (1.5 mm slice thickness) in 10 epilepsy patients.
  • Inclusion of diverse lesional epilepsy types: head injury, hippocampal sclerosis, low-grade glioma, dysembryoplastic neuroepithelial tumor, polymicrogyria, perinatal infarct, and presumed thrombosed aneurysm.

Related Experiment Videos

Main Results:

  • Both 2D and 3D fast FLAIR sequences demonstrated superior lesion conspicuity compared to T1-weighted IRSPGR, except in polymicrogyria.
  • The 3D fast FLAIR sequence provided superior assessment of lesion extent, particularly for low-grade tumors.
  • 3D fast FLAIR imaging showed enhanced visualization of lesions in epilepsy patients.

Conclusions:

  • 3D fast FLAIR MRI is a valuable tool for epilepsy imaging.
  • This technique offers improved lesion detection and characterization, especially for low-grade tumors.
  • 3D fast FLAIR may enhance diagnostic accuracy in patients with lesional epilepsy.