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Synthesis and aldose reductase inhibitory activity of benzoyl-amino acid derivatives
S Benvenuti1, F Severi, L Costantino
1Dipartimento di Scienze Farmaceutiche, Università di Modena, Italy.
Abstract:
A series of N-(4-methoxy, 4-fluoro, 4-trifluoromethyl and 4-nitrobenzoyl)-L-amino acids was synthesized and their inhibitory activity towards bovine lens aldose reductase (ALR2) was tested.