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Metastatic uterine leiomyosarcoma presenting as a primary sarcoma of the parotid gland
A D Saiz1, U Sachdev, M L Brodman
1Department of Pathology, The Lillian and Henry M. Stratton-Hans Popper Mount Sinai School of Medicine, New York, New York 10029, USA.
Background:
Leiomyosarcoma of the uterus has a high metastatic potential to distant sites due to its tendency for hematogenous spread.
Case:
A 49-year-old woman presented with an enlarging parotid mass, diagnosed originally as a primary fibrosarcoma. Six years later, she developed pulmonary metastases and heavy, abnormal uterine bleeding. At hysterectomy, a uterine leiomyosarcoma, identical morphologically to the previous lesions, was identified. All tumors showed similar immunohistochemical staining, suggesting the metastatic nature of the original parotid tumor.
Conclusion:
This rare case of uterine leiomyosarcoma, presenting as a primary parotid sarcoma, underscores the importance of considering the possibility of a uterine primary tumor when a sarcoma arises in an organ in which these tumors are unusual.