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Acute intentional iron overdose in pregnancy
T Tran1, J R Wax, J D Steinfeld
1Department of Women's Health Services, Hartford Hospital, Connecticut, USA.
Obstetrics and Gynecology
|October 9, 1998
Summary
Acute iron overdose in pregnancy requires prompt management. Deferoxamine chelation in the third trimester is safe and potentially life-saving for both mother and fetus.
Area of Science:
- Obstetrics
- Toxicology
- Emergency Medicine
Background:
- Iron overdose is a significant concern in pregnancy, yet current obstetric literature lacks comprehensive management guidelines.
- Effective management strategies for acute iron poisoning during gestation are crucial.
Observation:
- A 27-year-old pregnant patient at 27 weeks' gestation attempted suicide by ingesting a substantial dose of elemental iron (24 mg/kg).
- The patient received immediate treatment including crystalloid hydration, gastric lavage, and intravenous deferoxamine chelation.
Findings:
- The implemented treatment regimen successfully managed the acute iron overdose.
- No adverse maternal or fetal complications were observed following the intervention.
Implications:
- Acute iron overdose management in pregnant patients should not differ from non-pregnant individuals.
- Deferoxamine administration during the third trimester of pregnancy is deemed safe and can be life-saving, without associated perinatal risks.