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Spirofungin, a new antifungal antibiotic from Streptomyces violaceusniger Tü 4113
A Höltzel1, C Kempter, J W Metzger
1Institut für Organische Chemie, Universität Tübingen, Germany.
The Journal of Antibiotics
|October 10, 1998
Abstract:
A new secondary metabolite was detected in the culture filtrate and extracts of Streptomyces violaceusniger Tü 4113 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. The compound named spirofungin has a polyketide-spiroketal structure and shows various antifungal activities, particularly against yeasts.